Osteonecrosis of the jaws in patients with bone metastasis receiving intravenous bisphosphonates. A rising concern

摘要

Osteonecrosis of the jaws (ONJ) is a recognized complication of bisphosphonates (BP) therapy in cancer patients with bone metastasis. We report 2 additional cases of ONJ in women with breast cancer after long-term exposure to BP, discussing some considerations about the presentation and management of this rare and new complication.