Efficacy and Safety of Linezolid Compared with Vancomycin in a Randomized, Double-Blind Study of Febrile Neutropenic Patients with Cancer

Branimir Jaksic; Giovanni Martinelli; Jaime Perez Oteyza; Charlotte S. Hartman; Linda B. Leonard; and Kenneth J. Tack

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Efficacy and Safety of Linezolid Compared with Vancomycin in a Randomized, Double-Blind Study of Febrile Neutropenic Patients with Cancer

机译：利奈唑胺与万古霉素相比在发热性中性粒细胞减少癌患者中的随机，双盲研究的有效性和安全性

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摘要

Background. Gram-positive pathogens can cause serious infections in neutropenic patients with cancer, and vancomycin therapy is often initiated empirically. Linezolid may offer an option for these patients.

机译：背景。革兰氏阳性病原体可以在中性粒细胞减少的癌症患者中引起严重感染，万古霉素治疗通常是凭经验开始的。利奈唑胺可能为这些患者提供选择。

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来源
《Clinical Infectious Diseases 》 |2006年第5期| 597-607| 共11页
作者
Branimir Jaksic; Giovanni Martinelli; Jaime Perez Oteyza; Charlotte S. Hartman; Linda B. Leonard; and Kenneth J. Tack;
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作者单位

Department of Medicine Merkur University Hospital Zagreb Croatia;

Instituto Europeo Di Oncologia Milan Italy;

Hospital Ramon y Cajal Madrid Spain;

Pfizer Ann Arbor Michigan;

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机译：替加环素与万古霉素或利奈唑胺治疗严重耐甲氧西林金黄色葡萄球菌或耐万古霉素肠球菌感染的疗效和安全性：一项三期，多中心，双盲，随机研究
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3. Randomized, double-blind, phase II, multicenter study evaluating the safety/tolerability and efficacy of JNJ-Q2, a novel fluoroquinolone, compared with linezolid for treatment of acute bacterial skin and skin structure infection. [J] . Covington P, Davenport JM, Andrae D, Antimicrobial agents and chemotherapy. . 2011 ,第12期

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7. Efficacy and Safety of Linezolid Compared with Vancomycin in a Randomized, Double-Blind Study of Febrile Neutropenic Patients with Cancer [O] . B. Jaksic, G. Martinelli, J. P. Oteyza, 2006

机译：线唑胺与万古霉素在癌症患者的随机性中性患者随机的双盲研究中相比毒性的疗效和安全性

Efficacy and Safety of Linezolid Compared with Vancomycin in a Randomized, Double-Blind Study of Febrile Neutropenic Patients with Cancer

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