Mechanisms of selective head cooling for resuscitating damaged neurons during post-ischemic reperfusion

摘要

Conclusion Selective head cooling for sex hours during postischemic reperfusion does improve neuronal morphological outcomes in terms of morphological changes. Objective To evaluate the efficacy and the mechanism of application of selective head cooling on neuronal Morphological damage during postischemic reperfusion in a rabbit model. Methods 168 New Zealand rabbits were randomized into three groups. groupⅠ(n = 24,(38±0.5)deg. C, Non-ischemic control]; GroupⅡ[n = 72,(38±0.5)deg. C, normothermic reperfusion]; GroupⅢ[n = 72, (28±0.5)deg. C selective head cooling, initiated at the beginning or reperfusion).