Study on Effect of Small Dosage Tripterygium Glycosides in Auxiliary Treatment of Intractable Still's Disease

摘要

Intractable Still's disease, namely the intractable systemic juvenile idiopathic arthritis (JIA) is a clinical difficulty of pediatrics, and so far there still lacks any special treatment. In virtue of the markedly anti-inflammatory and immunosuppres-sive effects of tripterygium glycosides (TG, product of Huangshi Pharmaceutical Factory, 10 mg/ tab), it is applied in treating many kinds of connective tissue diseases in China, and it has also been used to treat various types of JIA for many years. But systematic study on its clinical therapeutic effect to Still' s disease in children has not been reported till now. In this study, with prospective comparative analysis adopted, the author had studied the therapeutic effect of small dosage TG on JIA reported.