Increased Productivity through Dynamic Process Optimization in Sterile Facility 303 at Novartis Pharma Stein AG: C. Installation of a Camera for Ampoule Burn Marks in Sterile Facility Building 303

摘要

On the DRN code-ringing machine, a system was installed and qualified in November 2001 for the detection of burn marks in ampoule tips. Since the ampoules are ringed immediately after sealing, and the burn marks are thus covered up, inspection is only possible between these two steps. This installation monitors the product quality online, so that the system does not have to wait until the inspection procession before detecting an accumulation of burn marks, but displays them immediately in order for countermeasures to be taken. The camera for burn marks is a tool for the early detection of malfunctions and minimization of rejects.