Cover Picture: New Fluorinated Rhodamines for Optical Microscopy and Nanoscopy (Chem. Eur. J. 15/2010)

摘要

F is for fluorescence and fluorine The cover picture shows aqueous and methanolic solutions of the new photostable fluorinated rhodamines that emit green or orange light. Surprisingly, N′,N-bis(2,2,2-trifluoroethyl)rhodamines were found to undergo sulfonation that provided the hydrophilic fluorinated dyes. After introducing amino reactive sites, fluorinated rhodamines may be used as fluorescent labels for (bio)molecules in optical microscopy and nanoscopy with very high light intensities. Details of this fascinating research can be found in the Full Paper of by V. N. Belov, C. E. Eggeling, S. W. Hell et al. on the page 4477 ff. The authors are grateful to Mrs. I. Böttcher (Max-Planck-Institut für Biophysikalische Chemie, Göttingen, Germany) for creating the picture.