Reverse vesicles formed by hydrogen bonded arylamide-derived triammonium cyclophanes and hexaammoninm capsule

摘要

Hydrogen bonded rigid imine-based macrocycles and capsules have been reduced to cyclic triamines and two-layered hexa-amines, the triammonium and hexaammonium derivatives of which are revealed to form reverse vesicles in organic liquids of low polarity, which are characterized by SEM, AFM, (HR)TEM, DLS and XRD. Vesicles, microscopic capsules that enclose an aqueous volume with thin membranes of specific molecules or polymers, have drawn great attention due to their potential applications in drug and gene delivery, as nanoreactors, and as artificial cell membranes. Reverse vesicles consist of a solvent core of low polarity that is surrounded by a reverse membrane shell. As the organic counterparts to the "normal" vesicles in aqueous solution, reverse vesicles may also be potentially endowed with similar functions.