The organocatalytic addition of bis(arylsulfonyl)methane to α,β-unsaturated aldehydes and the synthesis of optically-enriched 3-methyl-alkanols

摘要

An indirect organocatalytic method for the P-methylation of α,β-unsaturated aldehydes that involves the addition of bis(arylsulfonyl)methane catalyzed by prolinol derivatives and further elimination of the chameleonic sulfonyl groups is presented.