Self-association based on orthogonal C=O…C=O interactions in the solid and liquid state

摘要

A network of orthogonal C=O…C=O interactions was identified in the X-ray crystal structure of an α,α-difluorocyclo-pentanone derivative. This finding inspired investigations of self-association driven by these weak dipolar interactions in apolar solvents, which was proven by ~1H NMR spectroscopy.