How far can hydroxyl radicals travel? An electrochemical study based on a DNA mediated electron transfer process

摘要

Using photocatalytic reactive nanoparticles and DNA composite modified gold electrodes, exploiting the sensitivity of DNAmediated electron transfer to base pair stacking, we examined the effects of DNA oxidation damage by photocatalytically generated hydroxyl radicals (·OH) on charge transfer efficiency and proposed an electrochemical technique to read the effective diffusing distance of ·OH.