Controlling the macrocycle size by the stoichiometry of the applied template ion

摘要

Reaction of 4-tert-butyl-2,6-diformylphenol with (1R,2R)- or (1S,2S)-1,2-diaminocyclohexane in the presence of 1 equivalent of Zn~(2+) ions leads to selective formation of a chiral 2 + 2 macrocycle. Application of 0.5 equivalent of Zn~(2+) ions under the same conditions leads to selective formation of a chiral 3 + 3 macrocycle, which forms a cavitand-shaped trinuclear double decker complex with Zn(II).