Supramolecular design of a bicomponent topochemical reaction between two non-identical molecules

摘要

We report the first design of a topochemical reaction between two non-identical reactants using a supramolecular chemistry approach. A coassembly of two sugar-based organogelators with complementary reacting motifs, viz. azides and alkynes, undergoes topochemical Huisgen reaction between them. Topochemical reactions, the reaction between preorganized reacting motifs in the crystal lattice, are attractive not only because they provide a basic understanding of mechanistic and geometrical details about a reaction, but also because they constitute a perfectly green chemical method as they avoid solvents, catalysts and other special reaction conditions.