ZrCl_2(η-C_5Me_5)_2-AIHCl_2·(THF)_2: efficient hydroalumination of terminal alkynes and cross-coupling of the derived alanes

摘要

Stabilized AIHCI_2 (THF)_2 hydroaluminates RC≡CH with exceptional chemo-, regio- and stereoselectivity under efficient ZrCI_2(η-C_5Me_5)_2 catalysis (2-5 mol%). The resulting vinyl alanes undergo palladium cross-coupling with a wide range of sp~2 electrophiles (aryl, hetero-aryl and vinyl halides/pseudohalides) in good to excellent yields.