A new method for the synthesis of Z-enediones via IBX-mediated oxidative rearrangement of 2-alkynyl alcohol systems

摘要

o-Iodoxybenzoic acid (IBX) was found to mediate the conversion of alpha-alkynyl alcohols into Z-enediones under notably mild conditions via a novel rearrangement mechanism (33-65% yield,13 examples).Within the past decade,IBX (o-iodoxybenzoic acid) has emerged as a powerful oxidant for several oxidative transformations.