In vitro anti-cancer activity and structure–activity relationships of natural products isolated from fruits of Panax ginseng

Wei Wang; Yuqing Zhao; Elizabeth R. Rayburn; Donald L. Hill; Hui Wang; Ruiwen Zhang

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In vitro anti-cancer activity and structure–activity relationships of natural products isolated from fruits of Panax ginseng

机译：人参果实天然产物的体外抗癌活性与构效关系

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摘要

Panax ginseng and its extracts have long been used for medical purposes; there is increasing interest in developing ginseng products as cancer preventive or therapeutic agents. The present study was designed to determine biological structure–activity relationships (SAR) for saponins present in Panax ginseng fruits.

机译：人参及其提取物长期以来一直被用于医疗目的。人们对开发人参产品作为癌症预防剂或治疗剂的兴趣日益浓厚。本研究旨在确定人参果实中皂苷的生物结构-活性关系（SAR）。

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《Cancer Chemotherapy and Pharmacology》 |2007年第5期|589-601|共13页
作者
Wei Wang; Yuqing Zhao; Elizabeth R. Rayburn; Donald L. Hill; Hui Wang; Ruiwen Zhang;
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作者单位

Department of Pharmacology and Toxicology Division of Clinical Pharmacology Cancer Pharmacology Laboratory University of Alabama at Birmingham Birmingham AL 35294 USA;

Department of Pharmacology and Toxicology Division of Clinical Pharmacology Cancer Pharmacology Laboratory University of Alabama at Birmingham Birmingham AL 35294 USA;

Department of Pharmacology and Toxicology Division of Clinical Pharmacology Cancer Pharmacology Laboratory University of Alabama at Birmingham Birmingham AL 35294 USA;

Department of Pharmacology and Toxicology Division of Clinical Pharmacology Cancer Pharmacology Laboratory University of Alabama at Birmingham Birmingham AL 35294 USA;

Department of Pharmacology and Toxicology Division of Clinical Pharmacology Cancer Pharmacology Laboratory University of Alabama at Birmingham Birmingham AL 35294 USA;

Department of Pharmacology and Toxicology Division of Clinical Pharmacology Cancer Pharmacology Laboratory University of Alabama at Birmingham Birmingham AL 35294 USA;

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原文格式 PDF
正文语种 eng
中图分类
关键词
Panax n ginseng; Chemical structure; Anticancer; Structure–activity relationship;

机译：人参;化学结构;抗癌性;构效关系;

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1. ESR Study on the Structure and Hydroxyl Radical-Scavenging Activity Relationships of Ginsenosides Isolated from Panax ginseng C.A.MEYER [J] . Ki Sung KANG, Takako YOKOZAWA, Noriko YAMABE Biological & pharmaceutical bulletin . 2007,第5期

机译：eSR研究与Panax人参分离的人参皂苷的结构和羟基自由基 - 清除活性关系C.Meyer
2. Structure and biological activities of the polysaccharides from the leaves, roots and fruits of Panax ginseng C.A. Meyer: An overview [J] . Yongxu Sun Carbohydrate Polymers: Scientific and Technological Aspects of Industrially Important Polysaccharides . 2011,第3期

机译：人参叶片，根和果实中多糖的结构和生物学活性Meyer：概述
3. In vitro anthelmintic activity of the crude hydroalcoholic extract of Piper cubeba fruits and isolated natural products against gastrointestinal nematodes in sheep [J] . de Paula Carlis Matheus Souza, Feboli Aline, de Laurentiz Antonio Carlos, Veterinary Parasitology . 2019,第期

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4. Anti-Cancer and Structure-Activity Relationship of Natural Polyacetylenes [C] . Soninkhishig Tsolmon, Yui Kurita, Si Won Hong, Annual and International Meeting of the Japanese Association for Animal Cell Technology . 2010

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5. Saturation Mutagenesis and Structure-Activity Relationship of a Natural Product Antibiotic. [D] . Tran, Hai Long. 2017

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6. Structure–Activity Relationship and Molecular Docking of Natural Product Library Reveal Chrysin as a Novel Dipeptidyl Peptidase-4 (DPP-4) Inhibitor: An Integrated In Silico and In Vitro Study [O] . Poonam Kalhotra, Veera C. S. R. Chittepu, Guillermo Osorio-Revilla, 2018

机译：结构与活性之间的关系和天然产物库的分子对接揭示了作为一种新型二肽基肽酶-4（DPP-4）抑制剂的菊花素：集成的计算机和体外研究。
7. ESR Study on the Structure and Hydroxyl Radical-Scavenging Activity Relationships of Ginsenosides Isolated from Panax ginseng C. A. MEYER [O] . Ki Sung Kang, Takako Yokozawa, Noriko Yamabe, 2007

机译：eSR研究与Panax人参C.A. Meyer分离的人参皂苷的结构和羟基自由基 - 清除活性关系

In vitro anti-cancer activity and structure–activity relationships of natural products isolated from fruits of Panax ginseng

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