A multicenter phase II study of biweekly paclitaxel and S-1 combination chemotherapy for unresectable or recurrent gastric cancer

Akihiro Nakajo; Shuichi Hokita; Sumiya Ishigami; Futoshi Miyazono; Tadaaki Etoh; Masahiro Hamanoue; Shigeho Maenohara; Toshimitsu Iwashita; Hideaki Komatsu; Kiyoharu Satoh; Kuniaki Aridome; Satoshi Morita; Shoji Natsugoe; Hiroya Takiuchi; Shyuji Nakano; Yoshihiko Maehara; Junichi Sakamoto; Takashi Aikou

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A multicenter phase II study of biweekly paclitaxel and S-1 combination chemotherapy for unresectable or recurrent gastric cancer

机译：每两周进行一次紫杉醇和S-1联合化疗治疗无法切除或复发的胃癌的多中心II期研究

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摘要

This Phase II study assessed the activity and safety of biweekly paclitaxel and oral S-1 as treatment for unresectable and recurrent gastric cancer. The maximum tolerated dose for this regimen had been established previously in a Phase I study performed in Japanese patients.

机译：这项II期研究评估了每两周一次紫杉醇和口服S-1作为不可切除和复发性胃癌的治疗方法的活性和安全性。该方案的最大耐受剂量先前已在日本患者中进行的I期研究中确定。

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来源
《Cancer Chemotherapy and Pharmacology》 |2008年第6期|1103-1109|共7页
作者
Akihiro Nakajo; Shuichi Hokita; Sumiya Ishigami; Futoshi Miyazono; Tadaaki Etoh; Masahiro Hamanoue; Shigeho Maenohara; Toshimitsu Iwashita; Hideaki Komatsu; Kiyoharu Satoh; Kuniaki Aridome; Satoshi Morita; Shoji Natsugoe; Hiroya Takiuchi; Shyuji Nakano; Yoshihiko Maehara; Junichi Sakamoto; Takashi Aikou;
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作者单位

Department of Surgical Oncology and Digestive Surgery Kagoshima University Graduate School of Medicine Mail Stop 8-35-1 Sakuragaoka Kagoshima 890-8520 Japan;

Department of Surgical Oncology and Digestive Surgery Kagoshima University Graduate School of Medicine Mail Stop 8-35-1 Sakuragaoka Kagoshima 890-8520 Japan;

Department of Surgical Oncology and Digestive Surgery Kagoshima University Graduate School of Medicine Mail Stop 8-35-1 Sakuragaoka Kagoshima 890-8520 Japan;

Department of Surgical Oncology and Digestive Surgery Kagoshima University Graduate School of Medicine Mail Stop 8-35-1 Sakuragaoka Kagoshima 890-8520 Japan;

First Department of Surgery Miyazaki University Miyazaki Japan;

Kagoshima Kouseiren Hospital Kagoshima Japan;

Kagoshima Kouseiren Hospital Kagoshima Japan;

Kitakyushu Medical Center Fukuoka Japan;

Sasebo City General Hospital Nagasaki Japan;

Department of Digestive Surgery Saga University Saga Japan;

Saiseikai Sendai Hospital Kagoshima Japan;

Health and Community Medicine Program Nagoya University Graduate School of Medicine Nagoya Japan;

Department of Surgical Oncology and Digestive Surgery Kagoshima University Graduate School of Medicine Mail Stop 8-35-1 Sakuragaoka Kagoshima 890-8520 Japan;

Second Department of Internal Medicine Osaka Medical College Osaka Japan;

First Department of Internal Medicine and Department of Biosystemic Science of Medicine Kyushu University Graduate School of Medicine Fukuoka Japan;

Department of Surgery and Science Kyushu University Graduate School of Medicine Fukuoka Japan;

Health and Community Medicine Program Nagoya University Graduate School of Medicine Nagoya Japan;

Department of Surgical Oncology and Digestive Surgery Kagoshima University Graduate School of Medicine Mail Stop 8-35-1 Sakuragaoka Kagoshima 890-8520 Japan;

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原文格式 PDF
正文语种 eng
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关键词
Advanced gastric cancer; Phase II; Paclitaxel; S-1; Chemotherapy;

机译：晚期胃癌;II期;紫杉醇;S-1;化学疗法;

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专利

1. A multicenter phase II study of combined chemotherapy with docetaxel, cisplatin, and S-1 in patients with unresectable or recurrent gastric cancer (KDOG 0601) [J] . KoizumiW., NakayamaN., TanabeS., Cancer chemotherapy and pharmacology. . 2012,第2期

机译：多中心紫杉醇，顺铂和S-1联合化疗治疗无法切除或复发的胃癌的多中心II期研究（KDOG 0601）
2. A multicenter phase II study of combined chemotherapy with docetaxel, cisplatin, and S-1 in patients with unresectable or recurrent gastric cancer (KDOG 0601) [J] . Wasaburo Koizumi, Norisuke Nakayama, Satoshi Tanabe, Cancer Chemotherapy and Pharmacology . 2012,第2期

机译：多中心紫杉醇，顺铂和S-1联合化疗对无法切除或复发的胃癌患者的多中心II期研究（KDOG 0601）
3. Multicenter phase II study of weekly paclitaxel plus S-1 combination chemotherapy in patients with advanced gastric cancer. [J] . Ueda Y, Yamagishi H, Ichikawa D, Gastric cancer: official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association . 2010,第3期

机译：紫杉醇联合S-1联合化疗治疗晚期胃癌的多中心II期研究。
4. Effects of Weekly Paclitaxel as a Second-Iine Anticancer Chemotherapy for Patients with Advanced and Recurrent Gastric Carcinoma [C] . Y. Sakurai, I. Yoshida, T. Masui, International Gastric Cancer Congress . 2005

机译：每周紫杉醇作为先进和复发性胃癌患者的二缘抗癌化疗的影响
5. Combination of Photodynamic Therapy and Chemotherapy for Cancer Treatment by Using Paclitaxel-Loaded Porphyrin-Shelled Nanoemulsions [D] . Chang, Enling. 2021

机译：用紫杉醇负载卟啉壳纳米乳液使用光动力治疗和化疗对癌症治疗的组合
6. P-170Biweekly S-1 and nab-paclitaxel as first-line chemotherapy in patients with unresectable or recurrent gastric cancer [O] . L. Yang, Y. Song, W. Zhang, -1

机译：P-170双周S-1和nab-紫杉醇作为不可切除或复发性胃癌患者的一线化疗
7. P-170 Biweekly S-1 and nab-paclitaxel as first-line chemotherapy in patients with unresectable or recurrent gastric cancer [O] . L. Yang, Y. Song, W. Zhang, 2016

机译：P-170 Biweekly S-1和NAB-PACLITAXEL作为患者的一线化疗，患者不可切除或复发胃癌

A multicenter phase II study of biweekly paclitaxel and S-1 combination chemotherapy for unresectable or recurrent gastric cancer

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