A phase II study of paclitaxel combined with infusional 5-fluorouracil and low-dose leucovorin for advanced gastric cancer

Chong Kun Im; Hei-Cheul Jeung; Sun Young Rha; Nae Choon Yoo; Sung Hoon Noh; Jae Kyung Roh; Hyun Cheol Chung

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A phase II study of paclitaxel combined with infusional 5-fluorouracil and low-dose leucovorin for advanced gastric cancer

机译：紫杉醇联合5-氟尿嘧啶和小剂量亚叶酸输注治疗晚期胃癌的II期研究

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The aim of this study was to investigate the efficacy and safety of the combination chemotherapy of paclitaxel, infusional 5-fluorouracil (5-FU) and leucovorin (FLT regimen) in advanced gastric cancer. The primary end point was the time to progression (TTP).

机译：这项研究的目的是研究紫杉醇，5-氟尿嘧啶（5-FU）和亚叶酸钙（FLT方案）联合化疗对晚期胃癌的疗效和安全性。主要终点是进展时间（TTP）。

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来源
《Cancer Chemotherapy and Pharmacology》 |2008年第2期|315-321|共7页
作者
Chong Kun Im; Hei-Cheul Jeung; Sun Young Rha; Nae Choon Yoo; Sung Hoon Noh; Jae Kyung Roh; Hyun Cheol Chung;
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作者单位

Cancer Metastasis Research Center Yonsei University College of Medicine 134 Shinchon-Dong Seodaemun-Ku CPO Box 8044 Seoul 120-752 Korea;

Cancer Metastasis Research Center Yonsei University College of Medicine 134 Shinchon-Dong Seodaemun-Ku CPO Box 8044 Seoul 120-752 Korea;

Cancer Metastasis Research Center Yonsei University College of Medicine 134 Shinchon-Dong Seodaemun-Ku CPO Box 8044 Seoul 120-752 Korea;

Cancer Metastasis Research Center Yonsei University College of Medicine 134 Shinchon-Dong Seodaemun-Ku CPO Box 8044 Seoul 120-752 Korea;

Cancer Metastasis Research Center Yonsei University College of Medicine 134 Shinchon-Dong Seodaemun-Ku CPO Box 8044 Seoul 120-752 Korea;

Cancer Metastasis Research Center Yonsei University College of Medicine 134 Shinchon-Dong Seodaemun-Ku CPO Box 8044 Seoul 120-752 Korea;

Cancer Metastasis Research Center Yonsei University College of Medicine 134 Shinchon-Dong Seodaemun-Ku CPO Box 8044 Seoul 120-752 Korea;

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正文语种 eng
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关键词
Paclitaxel; Advanced gastric cancer; 5-FU; Leucovorin;

机译：紫杉醇;晚期胃癌;5-FU;叶绿素;

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专利

1. A phase II study of paclitaxel combined with infusional 5-fluorouracil and low-dose leucovorin for advanced gastric cancer. [J] . Im CK, Jeung HC, Rha SY, Cancer chemotherapy and pharmacology. . 2008,第2期

机译：紫杉醇联合5-氟尿嘧啶和小剂量亚叶酸输注治疗晚期胃癌的II期研究。
2. Phase II study of biweekly paclitaxel plus infusional 5-fluorouracil and leucovorin as first-line chemotherapy in patients with advanced gastric cancer. [J] . Wang F, Wang Z, Zhou N, American Journal of Clinical Oncology: Cancer Clinical Trials . 2011,第4期

机译：每两周一次紫杉醇联合输注5-氟尿嘧啶和亚叶酸钙作为晚期胃癌患者的一线化疗的II期研究。
3. Phase ii multicentered study of low-dose everolimus plus cisplatin and weekly 24-hour infusion of high-dose 5-fluorouracil and leucovorin as first-line treatment for patients with advanced gastric cancer [J] . ShenY.-C., LiC.-P., YenC.-J., Oncology: International Journal of Cancer Research and Treatment . 2014,第2期

机译：低剂量依维莫司+顺铂的第二期多中心研究以及每周24小时大剂量5-氟尿嘧啶和亚叶酸钙的输注作为晚期胃癌患者的一线治疗
4. Phase I/II clinical trials on the effect of weekly paclitaxel (wPTX) and wPTX containing combination regimens for advanced and metastatic gastric cancer -ECRIN group studies [C] . Sakamoto J, Kodera Y, Kobayashi M, International Gastric Cancer Congress . 2009

机译：I / II期临床试验关于每周紫杉醇（WPTX）和WPTX含有晚期和转移性胃癌组合方案的临床试验 - 分泌组研究
5. A discrimination of success variables that indicate increased likelihood to achieve Phase III Commercialization or Technology Infusion from NASA funded Phase II Small Business Innovation Research. [D] . Ise, Carl A. 2012

机译：成功变量的判别，表明获得由NASA资助的第二阶段小型企业创新研究进行第三阶段商业化或技术注入的可能性增加。
6. A phase II study of paclitaxel weekly 24-hour continuous infusion 5-fluorouracil folinic acid and cisplatin in patients with advanced gastric cancer [O] . C Kollmannsberger, D Quietzsch, C Haag, 2000

机译：紫杉醇每周24小时连续输注5-氟尿嘧啶亚叶酸和顺铂治疗晚期胃癌的II期临床研究
7. A Phase II Study of Irinotecan with Bi-weekly, Low-dose Leucovorin and Bolus and Continuous Infusion 5-fluorouracil (Modified FOLFIRI) as Salvage Therapy for Patients with Advanced or Metastatic Gastric Cancer [O] . S.-G. Kim, S. Y. Oh, H.-C. Kwon, 2007

机译：伊替康与双每周，低剂量白杨和推注和连续输注5-氟尿嘧啶（改性Folfiri）作为先进或转移性胃癌的患者的救生疗法研究

A phase II study of paclitaxel combined with infusional 5-fluorouracil and low-dose leucovorin for advanced gastric cancer

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