Combination chemotherapy of biweekly irinotecan (CPT-11) plus tegafur/uracil (UFT) and leucovorin (LV) for patients with metastatic colorectal cancer: phase I/II study in Japanese patients

Koji Okabayashi; Hirotoshi Hasegawa; Yoshiyuki Ishii; Takashi Endo; Hiroki Ochiai; Tetsuro Kubota; Yuko Kitagawa

首页> 外文期刊>Cancer Chemotherapy and Pharmacology >Combination chemotherapy of biweekly irinotecan (CPT-11) plus tegafur/uracil (UFT) and leucovorin (LV) for patients with metastatic colorectal cancer: phase I/II study in Japanese patients

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Combination chemotherapy of biweekly irinotecan (CPT-11) plus tegafur/uracil (UFT) and leucovorin (LV) for patients with metastatic colorectal cancer: phase I/II study in Japanese patients

机译：每两周伊立替康（CPT-11）联合替加氟/尿嘧啶（UFT）和亚叶酸（LV）联合化疗治疗转移性结直肠癌的患者：日本患者的I / II期研究

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Purpose We aimed to evaluate the safety and efficacy of combination chemotherapy with biweekly irinotecan (CPT-11) plus oral tegafur/uracil (UFT) and leucovorin (LV) in patients with previously untreated metastatic colorectal adenocarcinoma in phase I/II setting.

机译：目的我们的目的是评估在I / II期接受过转移性结直肠腺癌治疗的患者中，每两周一次伊立替康（CPT-11）联合口服替加氟/尿嘧啶（UFT）和亚叶酸（LV）联合化疗的安全性和有效性。

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《Cancer Chemotherapy and Pharmacology》 |2009年第3期|p.501-507|共7页
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Koji Okabayashi; Hirotoshi Hasegawa; Yoshiyuki Ishii; Takashi Endo; Hiroki Ochiai; Tetsuro Kubota; Yuko Kitagawa;
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1. Combination chemotherapy of biweekly irinotecan (CPT-11) plus tegafur/uracil (UFT) and leucovorin (LV) for patients with metastatic colorectal cancer: phase I/II study in Japanese patients. [J] . Okabayashi K, Hasegawa H, Ishii Y, Cancer chemotherapy and pharmacology. . 2009,第3期

机译：转移性结直肠癌患者每两周一次依立替康（CPT-11）联合替加氟/尿嘧啶（UFT）和亚叶酸（LV）联合化疗：日本患者的I / II期研究。
2. 665 PUBLICATION Phase I/II study of 24-hour infusion of irinotecan (CPT-11) in combination with sequential oral leucovorin (LV) and uracil/tegafur (UFT) for patients with metastatic colorectal cancer [J] . European Journal of Cancer Supplements . 2005,第2期

机译：665出版物I / II期研究伊立替康（CPT-11）与序贯口服亚叶酸（LV）和尿嘧啶/替加氟（UFT）联合治疗转移性结直肠癌患者的24小时
3. Uracil-Tegafur and Oral Leucovorin Combined With Bevacizumab in Elderly Patients (Aged >= 75 Years) With Metastatic Colorectal Cancer: A Multicenter, Phase II Trial (Joint Study of Bevacizumab, Oral Leucovorin, and Uracil-Tegafur in Elderly Patients [J-BLUE] Study) [J] . Nishina Tomohiro, Moriwaki Toshikazu, Shimada Mitsuo, Clinical colorectal cancer . 2016,第3期

机译：转移性结直肠癌的老年患者（年龄≥75岁）中的尿嘧啶-替加氟和口服白三叶素联合贝伐单抗：一项多中心，II期试验（贝伐单抗，口服白三叶素和尿嘧啶-替加氟联合治疗老年患者[J-BLUE ]研究）
4. Locoregional hyperthermia in combination with chemotherapy for metastatic breast cancer patients: The Mammatherm- trial [C] . J.K. Jueckstock, B. Eberhardt, H.L. Sommer World congress on medical physics and biomedical engineering;International congress of the IUPESM . 2011

机译：局部热疗联合化疗治疗转移性乳腺癌患者：Mammatherm-试验
5. A phase Ib study of safety and pharmacokinetics of trastuzumab emtansine and pertuzumab in Japanese patients with HER2-positive metastatic breast cancer [D] . NOGUCHI, Emi 2019

机译：Ib期研究曲妥珠单抗氨丹宁和帕妥珠单抗在日本HER2阳性转移性乳腺癌患者中的安全性和药代动力学
6. Preliminary results of phase I trial of oral uracil/tegafur (UFT) leucovorin plus irinotecan and radiation therapy for patients with locally recurrent rectal cancer [O] . Masayoshi Yasui, Masataka Ikeda, Mitsugu Sekimoto, 2006

机译：口服尿嘧啶/替加氟尔（UFT）亚叶酸钙联合伊立替康和放射治疗局部复发性直肠癌的第一阶段试验的初步结果
7. Randomized phase II trial of TEGAFIRI (tegafur/uracil, oral leucovorin, irinotecan) compared with FOLFIRI (folinic acid, 5-fluorouracil, irinotecan) in patients with unresectable/recurrent colorectal cancer [O] . Kohei Shigeta, Hirotoshi Hasegawa, Koji Okabayashi, 2016

机译：TEGAFIRI（TEGAFUR / URACIL，ORALEUCOVORIN，IRINOTECAN）的随机阶段II试验与无可切除/复发结直肠癌患者的FOLFIRI（叶酸，5-氟尿嘧啶，Irinotecan）相比

Combination chemotherapy of biweekly irinotecan (CPT-11) plus tegafur/uracil (UFT) and leucovorin (LV) for patients with metastatic colorectal cancer: phase I/II study in Japanese patients

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