Oxidative Damage of the Extracts of Condensate, Particulate and Semivolatile Organic Compounds from Gasoline Engine Exhausts on Testicles of Rats

摘要

Oxidative damage induced by extracts of condensate, particulate matters and semivolatile organic compounds from gasoline engine exhausts were investigated in testicles of adult Sprague-Dawley rats. The results showed that gasoline engine exhaust could increase the contents of malondialdehyde and carbonyl protein, decrease activities of superoxide dismutase and glutathione peroxidase, and induce DNA damage in testicle of rat. Taking together, the gasoline engine exhaust could promote oxidative damage of bio-macromolecular in testicles of rat and oxidative stress might be an alternative mechanism for male reproductive function of male mammals. Keywords Gasoline engine exhaust - Testicle - Oxidative damage