Multivariate regression analysis on early mortality after orthotopic liver transplantion

摘要

AIM: To identify the risk factors relating to early mortality after orthotopic liver transplantation. METHODS: Clinical data of 37 adult patients undergoing liver transplantation were retrospectively collected and divided into two groups: the survived group ( survival time 30 d) and the death group (survival time< 30 d). The relationship between multivariate risk factors and early mortality after orthotopic liver transplantation were analyzed by stepwise logistic regression. RESULTS: The survival rate was 73%. Early mortality rate was 27%. APACAE Ⅲ, preoperative serum creatinine level and interoperative bleeding quantity had a significant independent association with early mortality. ( R = 0.1841, 0.2056 and 0.3738). CONCLUSION: APACHE Ⅲ, preoperative serum creatinine level and interoperative bleeding quantity are significant risk factors relating to early mortality after orthotopic liver transplantation. To improve the recipient's preoperative critical condition and renal function and to reduce interoperative bleeding quantity could lower the early mortality after orthotopic liver transplantation.