Sentinel lymph node biopsy

摘要

Sentinel lymph node biopsy has developed over the past decade as a minimally invasive technique to assess regional lymph node status in patients with malignancy. This technique allows us to find out the status of a lymph node basin by removing only a small number of nodes. These nodes stand sentry to the rest of the nodal basin: if malignant disease is going to affect a nodal region it must first pass through the sentinel node. Therefore the nodal basin will contain malignant cells only if the sentinel node is first involved. The specific and limited removal of the sentinel node reduces surgical insult and morbidity compared with conventional lymphatic clearance. Sentinel lymph node biopsy is now widely available, and most cancer surgeons offer this as part of their diagnostic protocol for patients.