An electronic device for triggering a stimulator during membrane responsiveness determinations in cardiac tissues

摘要

A device is described that monitors the repolarization phase of a cardiac action potential and compares the membrane potential to a voltage selected by the investigator. When the voltages are the same, the device triggers a stimulator that injects the stimulus at the desired membrane potential. The device can stimulate tissue at any membrane potential during the repolarization phase of the action potential between 0 and -100 mV without regard to action potential duration. When it is precisely calibrated, its accuracy is within +or-1.0 mV.