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Design and experimental evaluation of an intracavitary ultrasound phased array system for hyperthermia

机译:腔内超声相控阵热疗系统的设计和实验评估

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摘要

For evaluating the feasibility of treating prostate cancer, a 64-element linear ultrasound phased array applicator for intracavitary hyperthermia was designed and constructed. A 64-channel ultrasound driving system including amplifiers, phase shifters, and RF power meters was also developed to drive the array. The design of the array and driving equipment are presented, as are the results of acoustical field measurements and in vitro perfused phantom studies performed with the array. Several techniques for heating realistically sized tumor volumes were also investigated, including single focus scanning and two techniques for producing multiple stationary foci. The results show that the operation of the array correlated closely with the theoretical model. When producing a single stationary focus, the array was able to increase tissue temperature by 12/spl deg/C in vitro in perfused phantom. With some minor improvements in array design, intracavitary phased arrays could be evaluated in a clinical environment.
机译:为了评估治疗前列腺癌的可行性,设计并构建了一种用于腔内热疗的64元线性超声相控阵喷药器。还开发了包括放大器,移相器和RF功率计的64通道超声驱动系统来驱动阵列。介绍了阵列和驱动设备的设计,以及阵列进行的声场测量和体外灌注体模研究的结果。还研究了几种加热现实大小肿瘤的技术,包括单焦点扫描和两种产生多个固定灶的技术。结果表明,阵列的操作与理论模型密切相关。当产生单个固定焦点时,阵列在灌注的体模中能够在体外将组织温度提高12 / spl deg / C。随着阵列设计的一些小改进,腔内相控阵列可以在临床环境中进行评估。

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