The effects of golimumab on radiographic progression in rheumatoid arthritis: Results of randomized controlled studies of golimumab before methotrexate therapy and golimumab after methotrexate therapy

Paul Emery; Roy Fleischmann; Désirée van der Heijde; Edward C. Keystone; Mark C. Genovese; Philip G. Conaghan; Elizabeth C. Hsia; Weichun Xu; Anna Baratelle; Anna Beutler; Mahboob U. Rahman

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The effects of golimumab on radiographic progression in rheumatoid arthritis: Results of randomized controlled studies of golimumab before methotrexate therapy and golimumab after methotrexate therapy

机译：戈利木单抗对类风湿关节炎放射学进展的影响：甲氨蝶呤治疗前戈利木单抗和甲氨蝶呤治疗后戈利木单抗的随机对照研究结果

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摘要

To evaluate the effects of golimumab on radiographic progression in patients with rheumatoid arthritis (RA).

机译：评估戈利木单抗对类风湿关节炎（RA）患者放射学进展的影响。

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《Arthritis & Rheumatism》 |2011年第5期|1200-1210|共11页
作者
Paul Emery; Roy Fleischmann; Désirée van der Heijde; Edward C. Keystone; Mark C. Genovese; Philip G. Conaghan; Elizabeth C. Hsia; Weichun Xu; Anna Baratelle; Anna Beutler; Mahboob U. Rahman;
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University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit Leeds UK;

University of Texas Southwest Medical Center at Dallas;

Leiden University Medical Center Leiden The Netherlands;

University of Toronto and Mount Sinai Hospital Toronto Ontario Canada;

Stanford University Palo Alto California;

Centocor Research and Development Inc. Malvern Pennsylvania and University of Pennsylvania School of Medicine Philadelphia;

Centocor Research and Development Inc. Malvern Pennsylvania;

Baratelle and Associates LLC Springfield Pennsylvania;

Pfizer Collegeville Pennsylvania;

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1. The effects of golimumab on radiographic progression in rheumatoid arthritis: results of randomized controlled studies of golimumab before methotrexate therapy and golimumab after methotrexate therapy. [J] . Emery P, Fleischmann R, van der Heijde D, Arthritis and Rheumatism . 2011,第5期

机译：戈利木单抗对类风湿关节炎放射学进展的影响：甲氨蝶呤治疗前戈利木单抗和甲氨蝶呤治疗后戈利木单抗的随机对照研究结果。
2. Erratum: Golimumab, a human anti-tumor necrosis factor monoclonal antibody, injected subcutaneously every four weeks in methotrexate-naive patients with active rheumatoid arthritis: Twenty-four-week results of a phase III, multicenter, randomized, double-blind, placebo-controlled study of golimumab before methotrexate as first-line therapy for early-onset rheumatoid arthritis [J] . li id=au1Paul Emery li id=au2Roy M. Fleischmann li id=au3Larry W. Moreland li id=au4Elizabeth C. Hsia li id=au5Ingrid Strusberg li id=au6Patrick Durez li id=au7Peter Nash li id=au8Eric Jason B. Amante li id=au9Melvin Churchill li id=au10Won Park li id=au11Bernardo Antonio Pons-Estel li id=au12Mittie K. Doyle li id=au13Sudha Visvanathan li id=au14Weichun Xu li id=au15Mahboob U. Rahman Arthritis & Rheumatism . 2010,第9期

机译：勘误：Golimumab，一种人类抗肿瘤坏死因子单克隆抗体，每隔四周皮下注射一次未接受甲氨蝶呤的活动性类风湿性关节炎患者：三期，多中心，随机，双盲，安慰剂治疗二十三周的结果氨甲蝶呤前戈利木单抗作为早期治疗类风湿关节炎的一线治疗的对照研究
3. Golimumab, a Human Anti-Tumor Necrosis Factor alpha Monoclonal Antibody, Injected Subcutaneously Every Four Weeks in Methotrexate-Naive Patients With Active Rheumatoid Arthritis Twenty-Four-Week Results of a Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Golimumab Before Methotrexate as First-Line Therapy for Early-Onset Rheumatoid Arthritis (vol 60, pg 2272, 2009) [J] . Emery Arthritis and Rheumatism . 2010,第9期

机译：Golimumab是一种人类抗肿瘤坏死因子α单克隆抗体，每四周一次皮下注射纯净甲氨蝶呤的活动性类风湿性关节炎患者，III期，多中心，随机，双盲，安慰剂对照研究的二十四周结果甲氨tre呤之前戈利木单抗作为早期治疗类风湿关节炎的一线治疗方法的研究（第60卷，第2272页，2009年）
4. Closed-loop Control For Rescue By Loucovorin In High-dose Methotrexate Chemotherapy [C] . Sano, A., Suzuki, Engineering in Medicine and Biology Society, 1990., Proceedings of the Twelfth Annual International Conference of the IEEE . 1990

机译：Loucovorin在大剂量甲氨蝶呤化疗中抢救的闭环控制
5. Development and characterization of methotrexate loaded poly(L-lactic acid) microspheres for the treatment of rheumatoid arthritis. [D] . Liang, Sanching Linda. 2006

机译：甲氨蝶呤负载聚（L-乳酸）微球的开发和表征，用于治疗类风湿关节炎。
6. Clinical efficacy radiographic progression and safety through 156 weeks of therapy with subcutaneous golimumab in combination with methotrexate in Japanese patients with active rheumatoid arthritis despite prior methotrexate therapy: final results of the randomized GO-FORTH trial [O] . Yoshiya Tanaka, Masayoshi Harigai, Tsutomu Takeuchi, -1

机译：尽管有甲氨蝶呤治疗但活动性类风湿性关节炎日本患者经皮下Golimumab联合甲氨蝶呤治疗156周后的临床疗效影像学进展和安全性：GO-FORTH随机试验的最终结果
7. The effects of golimumab on radiographic progression in rheumatoid arthritis: Results of randomized controlled studies of golimumab before methotrexate therapy and golimumab after methotrexate therapy [O] . Paul Emery, Roy Fleischmann, Désirée van der Heijde, 2011

机译：Golimalab对类风湿性关节炎射线照相进展的影响：甲氨蝶呤治疗甲氨蝶呤治疗前Golimalab随机对照研究的结果

The effects of golimumab on radiographic progression in rheumatoid arthritis: Results of randomized controlled studies of golimumab before methotrexate therapy and golimumab after methotrexate therapy

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