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Development of diagnostics for aquaculture: challenges and opportunities

机译:水产养殖诊断技术的发展:挑战与机遇

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The application of biotechnology in aquaculture has enabled the development and improvement of a wide range of immunodiagnostic and molecular technologies, and reagents and commercial kits have become more generally available. Recently, method development has increased exponentially as techniques used for clinical and veterinary medicine are adapted and optimized for use in aquaculture. Careful consideration needs to be given to selecting which rapid diagnostic methods to take forward and apply in aquaculture – pathogen detection methods need to be robust yet sensitive, and in many cases, capable of detecting a high degree of heterogeneity. There are numerous innovative techniques that may fulfil these criteria and provide valuable diagnostic tools. It is also important, however, that useful diagnostic methods already developed are standardized and fully validated, and that new technologies do not supercede these just because they are novel methods. The cost, speed, specificity and sensitivity of assays are all extremely important to end-users. This paper looks at some of the opportunities and challenges for the development of rapid diagnostics for aquaculture.
机译:生物技术在水产养殖中的应用使广泛的免疫诊断和分子技术的开发和改进成为可能,并且试剂和商业试剂盒也变得越来越普遍。近来,随着对用于临床和兽医学的技术进行调整和优化以用于水产养殖,方法的开发呈指数增长。在选择哪种快速诊断方法以应用于水产养殖中时,需要仔细考虑-病原体检测方法必须健壮而灵敏,并且在许多情况下必须能够检测高度异质性。有许多创新技术可以满足这些条件并提供有价值的诊断工具。但是,同样重要的是,已经开发出的有用的诊断方法已经过标准化并且得到了充分验证,并且新技术也不能仅仅因为它们是新颖的方法就可以取代这些诊断方法。测定的成本,速度,特异性和敏感性对最终用户而言都极为重要。本文着眼于发展水产养殖快速诊断的一些机遇和挑战。

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