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Strategy for prevention of cancers of the esophagus

机译:预防食道癌的策略

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摘要

The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on the animal reflux-inflammation models for Barrett's esophagus and esophageal adenocarcinoma; genomic/epigenomic analyses; eflornithine-based combinations; the molecular derangements that promote neoplastic transformation; the role of COX-2 inhibitors, proton pump inhibitors, and phase Ⅱ trials in Barrett's adenocarcinoma; statins in chemo-prevention and treatment of esophageal cancer; and biomarkers as potential targets in Barrett's adenocarcinoma.
机译:以下来自第十二届OESO世界会议:食道癌,包括有关Barrett食道和食道腺癌的动物反流-炎症模型的评论;基因组/表基因组分析;基于依弗鸟氨酸的组合;促进肿瘤转化的分子排列; COX-2抑制剂,质子泵抑制剂和Ⅱ期试验在巴雷特腺癌中的作用他汀类药物在食道癌的化学预防和治疗中;和生物标志物作为Barrett腺癌的潜在靶标。

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  • 来源
    《Annals of the New York Academy of Sciences》 |2014年第2014期|108-126|共19页
  • 作者单位

    National Center for Global Health and Medicine, Tokyo, Japan;

    Norwich Medical School, University of East Anglia, Norwich, United Kingdom,Department of Gastroenterology, Norfolk & Norwich University Hospital NHS Foundation Trust, Norwich, United Kingdom;

    Division of Gastroenterology & Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota;

    Division of Gastroenterology & Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota;

    Division of Gastroenterology & Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota;

    Norwich Medical School, University of East Anglia, Norwich, United Kingdom;

    Norwich Medical School, University of East Anglia, Norwich, United Kingdom,Department of Gastroenterology, Norfolk & Norwich University Hospital NHS Foundation Trust, Norwich, United Kingdom;

    Division of Cancer Prevention & Population Sciences, MD Anderson Cancer Center, Houston, Texas;

    Department of Surgery and Surgical Research, Medical University of Vienna, Vienna, Austria;

    Department of Surgery and Surgical Research, Medical University of Vienna, Vienna, Austria;

    Oncology Group, Academisch Medisch Centrum, Universiteit van Amsterdam, Amsterdam, the Netherlands;

    Division of Gastroenterology & Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota;

    Division of Gastroenterology & Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota;

    Oncology Group, Academisch Medisch Centrum, Universiteit van Amsterdam, Amsterdam, the Netherlands;

    Division of Gastroenterology and Hepatology, Stanford University, Stanford, California;

    National Center for Global Health and Medicine, Tokyo, Japan;

    Department of Surgery and Surgical Research, Medical University of Vienna, Vienna, Austria;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    animal reflux-inflammation models; Barrett's adenocarcinoma; elofrnithine; COXIBs, PPIs; statins; biomarkers; OESO;

    机译:动物反流-炎症模型;巴雷特腺癌;依氟鸟氨酸;COXIB;PPI;他汀类药物;生物标志物比索;

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