The Role of Growth Differentiation Factor-9 (GDF-9) and Its Analog, GDF-9b/BMP-15, in Human Breast Cancer

S. Hanavadi MS FRCS; T. A. Martin PhD; G. Watkins HND; R. E. Mansel MS FRCS; W. G. Jiang MB BCh MD

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The Role of Growth Differentiation Factor-9 (GDF-9) and Its Analog, GDF-9b/BMP-15, in Human Breast Cancer

机译：生长分化因子9（GDF-9）及其类似物GDF-9b / BMP-15在人乳腺癌中的作用

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There has been a recent surge of interest in the role of growth differentiation factors and other bone morphogenic proteins in the development and spread of cancer. In this study we have provided evidence that highlights the significance of growth and differentiation factor-9a (GDF-9a) and GDF-9b (bone morphogenic protein-15, BMP-15) in breast cancer development and progression.

机译：最近，人们对生长分化因子和其他骨形态发生蛋白在癌症的发展和扩散中的作用产生了浓厚的兴趣。在这项研究中，我们提供了证据，突出了生长和分化因子9a（GDF-9a）和GDF-9b（骨形态发生蛋白15，BMP-15）在乳腺癌发展和进展中的重要性。

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来源
《Annals of Surgical Oncology》 |2007年第7期|2159-2166|共8页
作者
S. Hanavadi MS FRCS; T. A. Martin PhD; G. Watkins HND; R. E. Mansel MS FRCS; W. G. Jiang MB BCh MD;
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作者单位

Metastasis and Angiogenesis Research Group Wales College of Medicine Cardiff University Cardiff UK;

Metastasis and Angiogenesis Research Group Wales College of Medicine Cardiff University Cardiff UK;

Metastasis and Angiogenesis Research Group Wales College of Medicine Cardiff University Cardiff UK;

Metastasis and Angiogenesis Research Group Wales College of Medicine Cardiff University Cardiff UK;

Metastasis and Angiogenesis Research Group Wales College of Medicine Cardiff University Cardiff UK;

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正文语种 eng
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关键词
Growth differentiation factor-9; Bone morphogenic protein-15; Breast cancer; Prognosis; Survival;

机译：生长分化因子9骨形态发生蛋白15乳腺癌预后生存;

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1. The role of growth differentiation factor-9 (GDF-9) and its analog, GDF-9b/BMP-15, in human breast cancer. [J] . Hanavadi S, Martin TA, Watkins G, Annals of surgical oncology . 2007,第7期

机译：生长分化因子9（GDF-9）及其类似物GDF-9b / BMP-15在人乳腺癌中的作用。
2. Relationship between the concentration of bone morphogenetic protein-15 (BMP-15) and growth differentiation factor-9 (GDF-9) in pre-ovulatory follicles, ovarian cysts and serum in sows [J] . Stankiewicz Tomasz, Blaszczyk Barbara Animal Production Science . 2016,第1期

机译：母猪排卵前卵泡，卵巢囊肿和血清中骨形态发生蛋白15（BMP-15）浓度与生长分化因子9（GDF-9）的关系
3. Loss of expression of growth differentiation factor-9 (GDF9) in human kidney cancer and regulation of growth and migration of kidney cancer cells by GDF9 [J] . DuP., YeL., LiH., Anticancer Research: International Journal of Cancer Research and Treatment . 2012,第10期

机译：人类肾癌中生长分化因子9（GDF9）的表达缺失以及GDF9对肾癌细胞生长和迁移的调节
4. Measurement of Human Breast Tumor Cell-Secreted shNDPK-B in a Murine Breast Cancer Model Suggests its Role in Metastatic Progression [C] . Nucharee Yokdang, Noah D. Buxton and lain L. 0. Buxton* Western Pharmacology Society . 2009

机译：在鼠乳腺癌模型中的人乳腺肿瘤细胞分泌的ShNDPK-B的测量表明其在转移性进展中的作用
5. Characterization of BIX-01294, its analogs E67 and E11 on growth, and reactivation of epigenetically silenced tumor suppressor genes in human breast cancer cells [D] . Pattabiraman, Vaishnavi. 2011

机译：BIX-01294及其类似物E67和E11的生长特性以及人乳腺癌细胞中表观遗传沉默的肿瘤抑制基因的激活
6. Role of CD31/Platelet Endothelial Cell Adhesion Molecule-1 Expression in in Vitro and in Vivo Growth and Differentiation of Human Breast Cancer Cells [O] . Luisella Righi, Silvia Deaglio, Carla Pecchioni, 2003

机译：CD31 /血小板内皮细胞粘附分子-1表达在人乳腺癌细胞体外和体内生长和分化中的作用
7. Concentrations of bone morphogenetic protein-15 (BMP-15) and growth differentiation factor-9 (GDF-9) in follicular cysts, mono - and polyoocyte follicles in gilts [O] . Tomasz Stankiewicz, Barbara Błaszczyk 2014

机译：胶囊囊肿，单核和多胞细胞卵泡中的骨形态发生蛋白-15（BMP-15）和生长分化因子-9（GDF-9）的浓度
8. Breast Cancer Prevention by Hormonally Induced Mammary Gland Differentiation: The Role of a Novel Mammary Growth Inhibitor and Differentiation Factor MRG (Addendum) [R] . Shi, Y. E. 2003

机译：通过激素诱导的乳腺分化预防乳腺癌：新型乳腺生长抑制剂和分化因子mRG的作用（附录）

The Role of Growth Differentiation Factor-9 (GDF-9) and Its Analog, GDF-9b/BMP-15, in Human Breast Cancer

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