The impact of inter-observer variation in pathological assessment of node-negative breast cancer on clinical risk assessmentn and patient selection for adjuvant systemic treatment

摘要

Background: It is well known that there is considerable inter-observer variability in assessment of the pathological parameters that are used to select node-negative breast cancer patients for adjuvant systemic treatment. There are only limited data available as to in how many patients this leads to differences in treatment decisions.