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首页> 外文期刊>American Journal of Tropical Medicine and Hygiene >Identification of Adenoviruses in Fecal Specimens from Wild Chimpanzees (Pan trogylodytes schweinfurthii) in Western Tanzania
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Identification of Adenoviruses in Fecal Specimens from Wild Chimpanzees (Pan trogylodytes schweinfurthii) in Western Tanzania

机译:在坦桑尼亚西部的野生黑猩猩(Pan trogylodytes schweinfurthii)的粪便样本中鉴定腺病毒

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摘要

DNA of two distinctive adenoviruses was detected in wild chimpanzees in western Tanzania that showed clinical signs of acute, upper respiratory disease, notably coughing. The amplified sequences from part of the capsid hexon gene suggests that one virus is a novel adenovirus serotype candidate and the other virus is a species C adenovirus most closely related to recent isolates from captive chimpanzees in the United States, Simian AdV 37 with 86% nucleic acid identity and Simian AdV 40 with 95% nucleic acid identity, respectively. The species C adenovirus sequences suggest possible recombination with a human adenovirus. The source of these viruses and disease association is not known.
机译:在坦桑尼亚西部的野生黑猩猩 中检测到两种独特的腺病毒的DNA,它们显示出急性,上呼吸道疾病的临床体征,尤其是咳嗽。从衣壳六邻体基因的一部分扩增的序列 表明,一种病毒是 一种新型腺病毒血清型候选物,另一种病毒是 种C腺病毒。与最近在美国圈养的黑猩猩的分离株 密切相关,具有86%核酸同一性的Simian AdV 37 和具有95%核酸的Simian AdV 40分别>酸身份。 C类腺病毒序列 建议与人腺病毒重组。这些病毒与疾病关联的 来源未知。

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    Gastroenteritis and Respiratory Viruses Laboratory Branch, Divisionof Viral Diseases, and Infectious Disease Pathology Branch,Division of Viral and Rickettsial Diseases, Centers for DiseaseControl and Prevention, Atlanta, Georgia;

    Department of BiomedicalSciences and Pathobiology, Virginia-Maryland Regional Collegeof Veterinary Medicine, Virginia Technology, Blacksburg, Virginia;

    Department of Microbiology, Research Centre of Infection andImmunology, and State Key Laboratory of Emerging InfectiousDiseases, The University of Hong Kong, Hong Kong, People's Republicof China;

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