Treatment of nocturnal airway obstruction improves daytime cognitive performance in asthmatics

摘要

It has been shown that asthmatics have nocturnal symptoms associated with impaired cognitive per- formance. We explored more carefully different therapeutic approaches on this performance in rela- tion to lung function in 46 atopics with mild to moderate asthma and with a circadian variation in peak expiratory flow (PEF) ≥15/100. In a double-blind, parallel study they inhaled salmeterol 50 μg or fluticasone 250 μg or a combination of both twice daily for 6 wk.