Increase of C-Reactive Protein and Decrease of Surfactant Protein A in Surfactant after Lung Transplantation

摘要

In this study, we asked whether the serum acute-phase protein C-reactive protein(CRP) increased in large surfactant aggregates after lung transplantation and analyzed the changes in composition and interfacial adsorption activity of those aggregates. Single left lung transplantation was performed in weight-matched pairs of dogs. A double-lung block from the donor animal was flushed with either modified Euro-Collins solution(EC) (n = 6) or University of Wisconsin solution (UW)(n = 6) at 4°C followed by immersion in cold EC of UW for 22h. the left donor lung was transplanted.