Clinical assay of N-duopropenide alcohol solution on hand application in newborn and pediatric intensive care units: control of an outbreak of multiresistant klebsiella pneumoniae in a newborn intensive care unit with this measure

摘要

Outbreak of gram-negative colonization(generally by antibiotic-resistant enterobacteria)are common in newborn intensive care units(NICUs), and control methods are not always effective. We studied the effectiveness of an alcohol solution of N-duopropenide(NDP)in vivo(germicidal effect on flora of teams in the NICU and the pediatric care unit vs handwashing with nonantiseptic soap)and its effect on the control of a multiresis- tant(MR)Klebsiella pneumoniae outbreak in our NICU that had persisted for 13 months, despite the use of classic control measures.