Calcium Supplementation and Osteoporosis Prevention

摘要

Tang and colleagues conducted a meta-analysis to determine the effectiveness of calcium therapy, with or without vitamin D supplementation, to prevent osteoporotic bone loss and fracture. Overall, the 17 trials using fracture as an outcome (n = 52,625) reported a consistent and highly significant 12 percent risk reduction in patients treated with calcium with or without vitamin D supplementation, and the 24 trials studying bone mineral density reported highly significant reductions in bone loss at the hip and spine.