Review: Based on evidence from higher-quality trials, chondroitin does not reduce pain in knee or hip osteoarthritis

摘要

Because no currently available medical therapy can reverse or slow thenprogression of knee and hip OA, many patients use nutriceuticals, such asnglucosamine and chondroitin, to treat their pain. Expectations for thesenagents are based on the fact that OA involves loss of articular cartilage, andnchondroitin is the predominant glycosaminoglycan (GAG) component ofnarticular cartilage and glucosamine is an important GAG precursor.