Review: Nonselective nonsteroidal antiinflammatory drugs do not increase risk for cardiovascular events

摘要

The recognition that such traditional “nonselective” NSAIDs as ibuprofen,ndiclofenac, and others exhibit varying effects on the cyclooxygenasen2 (COX-2) isoform has raised legitimate questions about whether thesendrugs might increase cardiovascular risk in a manner similar to thenCOX-2–selective NSAIDs.