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Use of 3D printers to create a patient‐specific 3D bolus for external beam therapy

机译:使用3D打印机创建特定于患者的3D推注以进行外部束治疗

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摘要

The purpose of this paper is to demonstrate that an inexpensive 3D printer can be used to manufacture patient‐specific bolus for external beam therapy, and to show we can accurately model this printed bolus in our treatment planning system for accurate treatment delivery. Percent depth‐dose measurements and tissue maximum ratios were used to determine the characteristics of the printing materials, acrylonitrile butadiene styrene and polylactic acid, as bolus material with physical density of 1.04 and 1.2g/cm3, and electron density of 3.38×1023electrons/cm3 and 3.80×1023electrons/cm3, respectively. Dose plane comparisons using Gafchromic EBT2 film and the RANDO phantom were used to verify accurate treatment planning. We accurately modeled a printing material in Eclipse treatment planning system, assigning it a Hounsfield unit of 260. We were also able to verify accurate treatment planning using gamma analysis for dose plane comparisons. With gamma criteria of 5% dose difference and 2 mm DTA, we were able to have 86.5% points passing, and with gamma criteria of 5% dose difference and 3 mm DTA, we were able to have 95% points passing. We were able to create a patient‐specific bolus using an inexpensive 3D printer and model it in our treatment planning system for accurate treatment delivery.PACS numbers: 87.53.Jw, 87.53.Kn, 87.56.ng
机译:本文的目的是证明可以使用便宜的3D打印机制造用于外部束治疗的特定于患者的推注,并表明我们可以在我们的治疗计划系统中准确模拟此打印推注,以实现准确的治疗。深度剂量百分比和组织最大比值用于确定印刷材料,丙烯腈丁二烯苯乙烯和聚乳酸的特性,这些材料是团聚材料,其物理密度为1.04,且 1.2 g / cm 3 3.38 × 10 23 电子 / cm 3 3.80 × 10 23 电子 / cm 3 ly。使用Gafchromic EBT2胶片和RANDO体模进行剂量平面比较,以验证准确的治疗计划。我们在Eclipse治疗计划系统中对打印材料进行了精确建模,将其分配为260的Hounsfield单位。我们还能够使用伽马分析对剂量平面比较来验证准确的治疗计划。在5%剂量差异和2 mm DTA的伽玛标准下,我们能够通过86.5%的点,在5%剂量差异和3 mm DTA的伽玛标准下,我们能够通过95%的点。我们能够使用廉价的3D打印机创建特定于患者的推注并将其建模到治疗计划系统中以实现准确的治疗.PACS编号:87.53.Jw,87.53.Kn,87.56.ng

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