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Epistemic modesty ostentatiousness and the uncertainties of epigenetics: on the knowledge machinery of (social) science

机译:认识论的谦虚夸张和表观遗传学的不确定性:在(社会)科学的知识机器上

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摘要

Epigenetic processes are garnering attention in the social sciences, where some scholars assert their importance for theorizing social life. I engage with such ideas here by drawing on interviews with leading bioscientists. To begin with, I underscore the (productive) uncertainties of those working in and around epigenetics; I describe these as a manifestation of ‘epistemic modesty’, and suggest that dissensus helps to propel biomedical innovation. Then, drawing on the concept of ‘alien science’, I detail some researchers’ ambivalences regarding the notion of ‘transgenerational inheritance’; their dissatisfaction with the (public) communication practices of other scientists (situated in what I term a regime of ‘epistemic ostentatiousness’); and the challenges faced when moderating societal discussion of epigenetics in ways that expand excitement whilst deflating (what researchers regard as) unrealistic expectations. The paper concludes with reflections on the knowledge machinery of the (social) sciences, and employs the study data to interrogate sociological engagements with epigenetics.
机译:表观遗传过程在社会科学中引起了人们的注意,其中一些学者断言其对于理论化社会生活的重要性。我在这里通过与领先的生物科学家的访谈来探讨这些想法。首先,我强调表观遗传学及其周围研究人员的(生产性)不确定性。我将这些描述为“适度的谦虚”的体现,并建议不同意见有助于推动生物医学创新。然后,我以“外来科学”的概念为基础,详细介绍了一些研究人员对“跨代继承”概念的歧义。他们对其他科学家的(公开的)交流实践不满意(我称之为“流行主义”制度);以及在扩大兴奋性,同时缩小(研究人员认为)不切实际的期望的方式来主持表观遗传学的社会讨论时所面临的挑战。本文以对(社会)科学知识机制的思考作为结束语,并利用研究数据对表观遗传学进行社会学研究。

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