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Addition of docetaxel to S-1 without platinum prolongs survival of patients with advanced gastric cancer: a randomized study (START)

机译：在没有铂的S-1中添加多西他赛可延长晚期胃癌患者的生存期：一项随机研究（START）

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摘要

Purpose Cisplatin plus 5-fluorouracil has been globally accepted as a standard regimen for the treatment for advanced gastric cancer. However, cisplatin has several disadvantages, including renal toxicity and the need for admission. S-1 plus cisplatin has become a standard treatment for advanced gastric cancer in East Asia. This phase III study was designed to evaluate the potential benefits of adding docetaxel to S-1 without a platinum compound in patients with advanced gastric cancer.

机译：目的顺铂加5-氟尿嘧啶已被全球公认为治疗晚期胃癌的标准方案。但是，顺铂有几个缺点，包括肾毒性和需要入院。 S-1加顺铂已成为东亚晚期胃癌的标准治疗方法。这项III期研究旨在评估在晚期胃癌患者中将多西他赛添加至不含有铂类化合物的S-1中的潜在益处。

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期刊名称 Springer Open Choice
作者
Wasaburo Koizumi; Yeul Hong Kim; Masashi Fujii; Hoon Kyo Kim; Hiroshi Imamura; Kyung Hee Lee; Takuo Hara; Hyun Cheol Chung; Taroh Satoh; Jae Yong Cho; Hisashi Hosaka; Akihito Tsuji; Akinori Takagane; Mikito Inokuchi; Kazuaki Tanabe; Tatsuya Okuno; Mariko Ogura; Kazuhiro Yoshida; Masahiro Takeuchi; Toshifusa Nakajima;
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作者单位

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年(卷),期 -1(140),2
年度 -1
页码 319–328
总页数 10
原文格式 PDF
正文语种
中图分类外科学;
关键词
Advanced gastric cancer Chemotherapy S-1 Docetaxel;

机译：晚期胃癌;化学疗法;S-1;多西他赛;

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专利

1. Addition of docetaxel to S-1 without platinum prolongs survival of patients with advanced gastric cancer: A randomized study (START) [J] . KoizumiW., KimY.H., FujiiM., Journal of Cancer Research and Clinical Oncology . 2014,第2期

机译：在没有铂的S-1中添加多西他赛可延长晚期胃癌患者的生存期：一项随机研究（START）
2. Addition of docetaxel to S-1 without platinum prolongs survival of patients with advanced gastric cancer: A randomized study (START) [J] . KoizumiW., KimY.H., FujiiM., Journal of Cancer Research and Clinical Oncology . 2014,第2期

机译：添加Docetaxel至S-1没有铂延长晚期胃癌患者的存活：随机研究（开始）
3. A randomized phase II study of a combination of docetaxel and S-1 versus docetaxel monotherapy in patients with non-small cell lung cancer previously treated with platinum-based chemotherapy: results of Okayama Lung Cancer Study Group (OLCSG) Trial 0503. [J] . Segawa Y, Kiura K, Hotta K, Journal of thoracic oncology: official publication of the International Association for the Study of Lung Cancer . 2010,第9期

机译：多西紫杉醇和S-1联合多西紫杉醇单药联合治疗非小细胞肺癌先前接受铂类化学疗法治疗的随机II期研究：冈山肺癌研究组（OLCSG）试验0503的结果。
4. S-1/CDDP/Lentinan Combination Chemotherapy for Inoperable Advanced Gastric Cancer [C] . Shoichi Nagahashi, Hidekazu Suzuki, Toshifumi Hib International Gastric Cancer Congress . 2005

机译：S-1 / CDDP / Lentinan组合化疗，可管理的胃癌无法操作
5. Clinical and Economic Outcomes for Gastric Cancer Patients Treated with Gastrectomy at Centres with and without Cancer Surgery Designation in Ontario [D] . Jeong, Yunni . 2019

机译：安大略省患有癌症手术指定胃癌治疗胃癌患者的胃癌患者的临床和经济结果
6. A Multicenter Randomized Phase II Study of Docetaxel vs. Docetaxel Plus Cisplatin vs. Docetaxel Plus S-1 as Second-Line Chemotherapy in Metastatic Gastric Cancer Patients Who Had Progressed after Cisplatin Plus Either S-1 or Capecitabine [O] . Keun-Wook Lee, Bum Jun Kim, Mi-Jung Kim, 2017

机译：多西他赛与多西他赛加顺铂与多西他赛加S-1作为转移性胃癌患者顺铂加S-1或卡培他滨治疗后的二线化疗的多中心随机II期研究
7. Addition of docetaxel to S-1 without platinum prolongs survival of patients with advanced gastric cancer: a randomized study (START) [O] . Wasaburo Koizumi, null null, Yeul Hong Kim, 2013

机译：在没有铂的S-1中添加多西他赛可延长晚期胃癌患者的生存期：一项随机研究（START）

Addition of docetaxel to S-1 without platinum prolongs survival of patients with advanced gastric cancer: a randomized study (START)

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