Safe and effective deodorization of malodorous fungating tumors using topical metronidazole 0.75  gel (GK567): a multicenter open-label phase III study (RDT.07.SRE.27013)

摘要

PurposeMalignant fungating tumors are neoplastic tumors associated with skin ulcers, which are susceptible to microbial colonization. Bacterial infection and proliferation may lead to malodor causing distress to patients. Metronidazole—an effective agent against anaerobes—may contribute to deodorization and improvement in quality of life (QOL). This study investigated the efficacy and safety of topical metronidazole 0.75 % gel for alleviation of malodor in anaerobically infected fungating neoplastic tumors.