Motivated by the di-photon excess at 750 GeV reported by the ATLAS and CMS experiments, we present an F-theory inspired flipped SO(10) model embedded in ℰ6. The low energy spectrum includes the three MSSM chiral families, vector-like colour triplets, several pairs of charged SU(2)L singlet fields , as well as MSSM singlets, one or more of which could contribute to the di-photon resonance. A total decay width in the multi-GeV range can arise from couplings involving the singlet and MSSM fields.
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