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High-throughput and direct measurement of androgen levels using turbulent flow chromatography liquid chromatography-triple quadrupole mass spectrometry (TFC-LC-TQMS) to discover chemicals that modulate dihydrotestosterone production in human prostate cancer cells

机译：使用湍流色谱液相色谱-三重四极杆质谱（TFC-LC-TQMS）高通量和直接测量雄激素水平以发现可调节人前列腺癌细胞中二氢睾丸激素产生的化学物质

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摘要

ObjectivesTo develop a high-throughput screening system to measure the conversion of testosterone to dihydrotestosterone (DHT) in cultured human prostate cancer cells using turbulent flow chromatography liquid chromatography-triple quadrupole mass spectrometry (TFC-LC-TQMS).

机译：目的使用湍流色谱-液相色谱-三重四极杆质谱（TFC-LC-TQMS），开发一种高通量筛选系统，以测量培养的人前列腺癌细胞中睾丸激素向二氢睾丸酮（DHT）的转化。

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期刊名称 Springer Open Choice
作者
Kyungsu Kang; Lei Peng; Yu-Jin Jung; Joo Yeon Kim; Eun Ha Lee; Hee Ju Lee; Sang Min Kim; Sang Hyun Sung; Cheol-Ho Pan; Yongsoo Choi;
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作者单位

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年(卷),期 -1(40),2
年度 -1
页码 263–270
总页数 8
原文格式 PDF
正文语种
中图分类外科学;
关键词
5α-reductase inhibitor Dihydrotestosterone Fucoxanthin Naringenin Testosterone;

机译：5α-还原酶抑制剂;二氢睾丸激素;岩藻黄质;柚皮素;睾丸激素;

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1. High-throughput and direct measurement of androgen levels using turbulent flow chromatography liquid chromatography-triple quadrupole mass spectrometry (TFC-LC-TQMS) to discover chemicals that modulate dihydrotestosterone production in human prostate cancer cells [J] . Kang Kyungsu, Peng Lei, Jung Yu-Jin, Biotechnology Letters . 2018,第2期

机译：使用湍流流体色谱液相色谱 - 三重四极杆质谱（TFC-LC-TQMS）的高通量和直接测量雄激素水平溶解，发现化学品调节人前列腺癌细胞中的二氢睾酮产生
2. High-throughput and direct measurement of androgen levels using turbulent flow chromatography liquid chromatography-triple quadrupole mass spectrometry (TFC-LC-TQMS) to discover chemicals that modulate dihydrotestosterone production in human prostate cancer cells [J] . Kang Kyungsu, Peng Lei, Jung Yu-Jin, Biotechnology Letters . 2018,第2期

机译：使用湍流流动色谱液相色谱 - 三重四极杆质谱（TFC-LC-TQMS）的高通量和直接测量雄激素水平探测化学品，用于调节人前列腺癌细胞中的二氢睾酮产生
3. Comparison of Chemical Constituents in Magnoliae Officinalis Cortex Processed by "Sweating" and "Non Sweating" based on Ultra Fast Liquid Chromatography-Triple Quadrupole-Time of Flight Mass Spectrometry and Gas Chromatography-Triple Quadrupole Mass Spectrometry Combined with Multivariate Statistical Analysis [J] . Zhao Hui, Yan Ying, Wang Cheng-cheng, Natural product communications . 2018,第8期

机译：基于超快速液相色谱 - 三重四极轴 - 飞行质谱和气相色谱 - 三重四极杆质谱与多变量统计分析相结合的基于超快速液相色谱 - 三重四极杆质谱 - 三重四极高升压力的化学成分对比较
4. Comparison of metabolomic profiles of androgen-dependent and refractory prostate cancer cells using liquid chromatography-mass spectrometry (LC-MS) [C] . Nagireddy Putluri, Shaiju Vareed, Theodore Sana, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2010

机译：使用液相色谱 - 质谱法（LC-MS）对雄激素依赖性和难治性前列腺癌细胞的代谢物谱比较
5. Analysis of polybrominated diphenyl ethers (PBDEs) by liquid chromatography with negative-ion atmospheric pressure photoionization tandem mass spectrometry (LC/NI-APPI/MS/MS). Measurement of PBDE levels in automobile dust and implications for human exposure. [D] . Oswald, Timothy D. 2008

机译：负离子大气压光电离串联质谱（LC / NI-APPI / MS / MS）液相色谱分析多溴二苯醚（PBDEs）。测量汽车灰尘中的多溴二苯醚含量及其对人体的影响。
6. Determination of Polyphenols in Ilex kudingcha and Insect Tea (Leaves Altered by Animals) by Ultra-high-performance Liquid Chromatography-Triple Quadrupole Mass Spectrometry (UHPLC-QqQ-MS) and Comparison of Their Anti-Aging Effects [O] . Jianfei Mu, Fuping Yang, Fang Tan, 2020

机译：通过超高效液相色谱 - 三重四极杆质谱（UHPLC-QQQ-MS）测定ILEX Kudingcha和昆虫茶（叶片改变的鸟胶）的聚酚（叶片）的测定并进行抗衰老效应的比较
7. High-throughput and direct measurement of androgen levels using turbulent flow chromatography liquid chromatography-triple quadrupole mass spectrometry (TFC-LC-TQMS) to discover chemicals that modulate dihydrotestosterone production in human prostate cancer cells [O] . Kyungsu Kang, Lei Peng, Yu-Jin Jung, 2017

机译：使用湍流流动色谱液相色谱 - 三重四极杆质谱（TFC-LC-TQMS）的高通量和直接测量雄激素水平探测化学品，用于调节人前列腺癌细胞中的二氢睾酮产生
8. Measurement of elemental speciation by liquid chromatography -- inductively coupled plasma mass spectrometry (LC-ICP-MS) with the direct injection nebulizer (DIN). [R] . Shum, S. 1993

机译：通过液相色谱 - 电感耦合等离子体质谱（LC-ICp-ms）和直接喷射雾化器（DIN）测量元素形态。

High-throughput and direct measurement of androgen levels using turbulent flow chromatography liquid chromatography-triple quadrupole mass spectrometry (TFC-LC-TQMS) to discover chemicals that modulate dihydrotestosterone production in human prostate cancer cells

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