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Role of contrast-enhanced ultrasound in evaluation of the bowel

机译:超声造影在肠评估中的作用

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摘要

Contrast-enhanced ultrasound (CEUS) of the gastrointestinal tract provides vascular information helpful for characterizing masses and other pathologies in and around the bowel, similar to contrast applications in other solid organs. However, the use of microbubble contrast agents for the bowel provides additional unique contributions as it gives both subjective and objective information about mural and mesenteric blood flow, invaluable for the determination of disease activity in those many patients affected by inflammatory bowel disease (IBD). IBD is a lifelong chronic disease and has its peak age of onset in adolescence or young adult life. Today, we have moved away from treating patient’s symptoms and strive instead to alter the course of disease by obtaining mucosal healing. Expensive and aggressive biologic therapies and lack of agreement of patient’s symptoms with their disease activity and complications necessitate frequent imaging surveillance, which must be safe, readily available, inexpensive, and effective. Ultrasound with the benefit of contrast enhancement meets these requirements and is shown in meta-analysis to be equivalent to CT and MRI scans for these indications.Electronic supplementary materialThe online version of this article (10.1007/s00261-017-1399-6) contains supplementary material, which is available to authorized users.
机译:胃肠道造影增强超声(CEUS)可提供血管信息,有助于表征肠内及周围的肿块和其他病变,类似于其他实体器官中的造影剂应用。然而,使用微泡造影剂为肠提供了额外的独特贡献,因为它提供了有关壁膜和肠系膜血流的主观和客观信息,对于确定许多受炎症性肠病(IBD)影响的患者的疾病活动而言,这是非常宝贵的。 IBD是一生的慢性疾病,其发病年龄以青春期或年轻成年期为最高。如今,我们已经从治疗患者的症状中摆脱出来,而是通过获得粘膜愈合来努力改变疾病进程。昂贵且激进的生物疗法以及患者症状与疾病活动和并发症的不一致,因此需要经常进行影像学检查,这必须是安全,容易获得,廉价且有效的。具有对比增强功能的超声符合这些要求,并且在荟萃分析中显示与这些适应症的CT和MRI扫描等效。电子补充材料本文的在线版本(10.1007 / s00261-017-1399-6)包含补充内容资料,可供授权用户使用。

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