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Should We Subtype ADHD According to the Context in Which Symptoms Occur? Criterion Validity of Recognising Context-Based ADHD Presentations

机译:我们是否应该根据出现症状的背景将多动症亚型化?识别基于上下文的ADHD演示文稿的标准有效性

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摘要

ADHD symptoms show considerable individual variation in the contexts in which they are expressed. It has previously been proposed that subtyping individuals according to the contexts in which symptoms are expressed may be clinically useful. We examined context-based patterns of ADHD symptoms in a longitudinal cohort study of n = 1388 children, as well as context-specific and context-general predictors of symptoms. Participants were community-ascertained and provided ADHD symptom data at ages 7, 9, and 11. Using growth mixture modelling we identified five inattention and five hyperactivity/impulsivity categories that differed in the developmental patterns of symptoms reported by parent and teacher informants. We found some evidence that context-specific predictors were related to context-specific expressions. Specifically, after controlling for other risk factors for ADHD symptoms, relationships with teachers predicted school-specific (teacher-reported) but not home-specific (parent-reported) symptom levels. However, no subtypes defined by exclusively home-based symptoms emerged, suggesting that while symptoms may sometimes be specific to the school context, they are only rarely confined to the home context. Subtyping by context could be informative; however, further work will required to uncover the nature of any etiological, functional, or outcome differences between those who show symptom expression in different contexts.Electronic supplementary materialThe online version of this article (10.1007/s10578-018-0842-4) contains supplementary material, which is available to authorized users.
机译:ADHD症状在其所表达的环境中显示出相当大的个体差异。先前已经提出根据表达症状的环境对个体进行分型可能在临床上是有用的。我们在一项对n = 1388名儿童进行的纵向队列研究中,研究了基于情境的ADHD症状模式,以及针对具体情境和症状的一般情境预测因素。参与者是社区确定的,并在7、9和11岁时提供了ADHD症状数据。使用生长混合物模型,我们确定了五种注意力不集中和五种活动过度/冲动类别,这些类别在家长和老师的举报者报告的症状发展模式上有所不同。我们发现一些证据表明,特定于上下文的预测因子与特定于上下文的表达有关。具体而言,在控制了多动症症状的其他危险因素后,与教师的关系预测了学校特有的(教师报告的)症状而非家庭特有的(父母报告的)症状水平。但是,没有出现仅由家庭症状定义的亚型,这表明尽管症状有时可能是特定于学校环境的,但很少会仅限于家庭环境。根据上下文进行分型可能会提供参考;但是,需要进一步的工作来揭示在不同情况下表现出症状表达的人之间在病因,功能或结局方面的差异的本质。电子补充材料本文的在线版本(10.1007 / s10578-018-0842-4)包含补充内容资料,可供授权用户使用。

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