Tuberculosis Treatment in HIV Infected Ugandans with CD4 Counts 350 Cells/mm3 Reduces Immune Activation with No Effect on HIV Load or CD4 Count

摘要

BackgroundBoth HIV and TB cause a state of heightened immune activation. Immune activation in HIV is associated with progression to AIDS. Prior studies, focusing on persons with advanced HIV, have shown no decline in markers of cellular activation in response to TB therapy alone.