A phantom study to assess the reproducibility, robustness and accuracy of PET image segmentation methods against statistical fluctuations

摘要

BackgroundAutomatic and semi-automatic segmentation methods for PET serve as alternatives to manual delineation and eliminate observer variability. The robustness of these segmentation methods against statistical fluctuations arising from variable size, contrast and noise are vital for providing reliable clinical outcomes for diagnosis and treatment response assessment. In this study, the performances of several segmentation methods have been investigated using the torso NEMA phantom against statistical fluctuations.