Cartilage defect location and stiffness predispose the tibiofemoral joint to aberrant loading conditions during stance phase of gait

摘要

ObjectivesThe current study quantified the influence of cartilage defect location on the tibiofemoral load distribution during gait. Furthermore, changes in local mechanical stiffness representative for matrix damage or bone ingrowth were investigated. This may provide insights in the mechanical factors contributing to cartilage degeneration in the presence of an articular cartilage defect.