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Tristetraprolin Inhibits Poly(A)-Tail Synthesis in Nuclear mRNA that Contains AU-Rich Elements by Interacting with Poly(A)-Binding Protein Nuclear 1

机译：Tristetraprolin通过与poly（A）结合蛋白Nuclear 1相互作用来抑制含有富AU元素的核mRNA中Poly（A）尾的合成。

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摘要

BackgroundTristetraprolin binds mRNA AU-rich elements and thereby facilitates the destabilization of mature mRNA in the cytosol.

机译：背景Tristetraprolin结合富含mRNA的AU元素，从而促进细胞溶质中成熟mRNA的不稳定。

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期刊名称 PLoS Clinical Trials
作者
Yu-Lun Su; Shun-Chang Wang; Pei-Yu Chiang; Nien-Yi Lin; Yu-Fang Shen; Geen-Dong Chang; Ching-Jin Chang;
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年(卷),期 2009(7),7
年度 2009
页码 e41313
总页数 15
原文格式 PDF
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专利

1. Structural and functional dissection of a conserved destabilizing element of cyclo-oxygenase-2 mRNA: evidence against the involvement of AUF-1 [AU-rich element/poly(U)-binding/degradation factor-1], AUF-2, tristetraprolin, HuR (Hu antigen R) or FBP1 (far-upstream-sequence-element-binding protein 1) [J] . Andrew R. CLARK, Gareth SULLY, Jeremy SAKLATVALA, The biochemical journal . 2004,第3期

机译：环氧合酶2 mRNA保守去稳定元件的结构和功能解剖：反对AUF-1 [AU-rich element / poly（U）-binding / degradation factor-1]，AUF-2，tristetraprolin， HuR（Hu抗原R）或FBP1（远上游序列元素结合蛋白1）
2. Phosphorylation of poly(rC) binding protein 1 (PCBP1) contributes to stabilization of mu opioid receptor (MOR) mRNA via interaction with AU-rich element RNA-binding protein 1 (AUF1) and poly A binding protein (PABP) [J] . Hwang Cheol Kyu, Wagley Yadav, Law Ping-Yee, Gene: An International Journal Focusing on Gene Cloning and Gene Structure and Function . 2017,第期

机译：聚（RC）结合蛋白1（PCBP1）的磷酸化有助于通过与富含Au富含元素RNA结合蛋白1（AUF1）的相互作用的Mu阿片类受体（Mor）mRNA的稳定化和聚结合蛋白（PABP）
3. Structural and functional dissection of a conserved destabilizing element of cyclo-oxygenase-2 mRNA: evidence against the involvement of AUF-1 [AU-rich element/poly(U)-binding/degradation factor-1], AUF-2, tristetraprolin, HuR (Hu antigen R) or FBP1 [J] . Sully G, Dean JLE, Wait R, The Biochemical Journal . 2004,第Pta3期

机译：保守的环氧合酶2 mRNA的结构和功能解剖：反对AUF-1 [AU-rich element / poly（U）-binding / degradation factor-1]，AUF-2，tristetraprolin， HuR（Hu抗原R）或FBP1
4. NTA-Functionalized Poly(L-lysine)-g-Poly(Ethylene Glycol): A Polymeric Interface for Binding and Studying 6 His-tagged Proteins [C] . Guoliang Zhen, S. Zurcher, D. Falconnet, . 2005

机译：NTA功能化的聚（L-赖氨酸）-g-聚（乙二醇）：绑定和研究6组His标签蛋白的聚合物界面。
5. Identification of host proteins interacting with potyviral RNA-dependent RNA polymerase and investigation of the roles of the carboxy terminus of cucumber poly-(A) binding protein 1 in potyviral replication and cellular translation. [D] . Wang, Xiaofeng. 2002

机译：鉴定与杯状病毒依赖RNA的RNA聚合酶相互作用的宿主蛋白，并研究黄瓜聚-（A）结合蛋白1的羧基末端在杯状病毒复制和细胞翻译中的作用。
6. Structural and functional dissection of a conserved destabilizing element of cyclo-oxygenase-2 mRNA: evidence against the involvement of AUF-1 AU-rich element/poly(U)-binding/degradation factor-1 AUF-2 tristetraprolin HuR (Hu antigen R) or FBP1 (far-upstream-sequence-element-binding protein 1). [O] . Gareth Sully, Jonathan L E Dean, Robin Wait, 2004

机译：保守的环氧合酶2 mRNA的结构和功能解剖：反对AUF-1 AU-rich element / poly（U）-binding / degradation factor-1AUF-2tristetraprolin HuR（Hu抗原R）或FBP1（远上游序列元素结合蛋白1）。
7. Tristetraprolin inhibits poly(A)-tail synthesis in nuclear mRNA that contains AU-rich elements by interacting with poly(A)-binding protein nuclear 1. [O] . Yu-Lun Su, Shun-Chang Wang, Pei-Yu Chiang, 2012

机译：Tristetraprolin通过与poly（a）结合蛋白核1相互作用抑制含有富含aU的元件的核mRNa中的poly（a）-tail合成。
8. The Effect of in Vivo Treatment with Triiodothyronine on the in Vitro Synthesis of Protein-Poly(ADP)-Ribose Adducts by Isolated Cardiocyte Nuclei and the Separation of Poly(ADP)-ribosylated Proteins by Phenol Extraction and Electr [R] . Jackowski, G., Kun, E. 1983

机译：三碘甲腺原氨酸体内处理对离体心肌细胞核体外合成蛋白质 - 聚（aDp） - 核糖加合物的影响及苯酚提取和电离分离聚（aDp） - 核糖基化蛋白

Tristetraprolin Inhibits Poly(A)-Tail Synthesis in Nuclear mRNA that Contains AU-Rich Elements by Interacting with Poly(A)-Binding Protein Nuclear 1

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