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Patterns of Gene Expression in Drosophila InsP3 Receptor Mutant Larvae Reveal a Role for InsP3 Signaling in Carbohydrate and Energy Metabolism

机译：果蝇InsP3受体突变体幼虫中的基因表达模式揭示了InsP3信号在碳水化合物和能量代谢中的作用。

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BackgroundThe Inositol 1,4,5-trisphosphate receptor (InsP3R) is an InsP3 gated intracellular Ca²⁺-release channel. Characterization of Drosophila mutants for the InsP3R has demonstrated that InsP3-mediated Ca²⁺ release is required in Drosophila larvae for growth and viability.

机译：背景肌醇1,4,5-三磷酸受体（InsP3R）是InsP3门控的细胞内Ca ^{2 + 释放通道。对果蝇InsP3R突变体的表征表明果蝇幼虫需要InsP3介导的Ca ^{2 + 释放才能生长和存活。}}

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期刊名称 PLoS Clinical Trials
作者
Satish Kumar; Debleena Dey; Gaiti Hasan;
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年(卷),期 2008(6),8
年度 2008
页码 e24105
总页数 12
原文格式 PDF
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1. Modulation of InsP3 receptor properties by phosphorylation: targeting of PKA to InsP3 receptors shapes oscillatory calcium signals in pancreatic acinar cells [J] . Giovannucci David R, Sneyd James, Groblewski Guy E, Journal of Korean medical science. . 2000,第Suppl期

机译：通过磷酸化调节InsP3受体特性：将PKA靶向InsP3受体可塑造胰腺腺泡细胞中的振荡钙信号
2. Inositol 1,4,5-Trisphosphate (InsP3) and Calcium Interact to Increase the Dynamic Range of InsP3 Receptor-dependent Calcium Signaling [J] . Edward J. Kaftan, Barbara E. Ehrlich, James Watras The Journal of general physiology . 1997,第5期

机译：肌醇1,4,5-三磷酸（InsP3）与钙相互作用可增加InsP3受体依赖性钙信号的动态范围
3. Suppression of InsP3 receptor-mediated Ca2+ signaling alleviates mutant presenilin-linked familial Alzheimer's disease pathogenesis [J] . ShillingD., MüllerM., TakanoH., The Journal of Neuroscience: The Official Journal of the Society for Neuroscience . 2014,第20期

机译：InsP3受体介导的Ca2 +信号转导的抑制减轻了早老素连锁的家族性阿尔茨海默氏病的发病机理
4. THE EFFECT OF SPACEFLIGHT ON DROSOPHILA ENERGY METABOLISM AND GENE EXPRESSION. [C] . Kanyan Xu International astronautical congress . 2013

机译：航天飞行对果蝇能量代谢和基因表达的影响。
5. The regulation of neuroregeneration in zebrafish (Danio rerio): Global gene expression patterns and the role of estrogen and arylhydrocarbon receptor (AhR) signaling. [D] . McCurley, Amy T. 2010

机译：斑马鱼（Danio rerio）中神经再生的调节：全局基因表达模式以及雌激素和芳基烃受体（AhR）信号的作用。
6. Modulation of InsP3 receptor properties by phosphorylation: targeting of PKA to InsP3 receptors shapes oscillatory calcium signals in pancreatic acinar cells. [O] . D R Giovannucci, J Sneyd, G E Groblewski, 2000

机译：通过磷酸化调节InsP3受体特性：将PKA靶向InsP3受体可塑造胰腺腺泡细胞中的振荡钙信号。
7. Patterns of Gene Expression in Drosophila InsP3 Receptor Mutant Larvae Reveal a Role for InsP3 Signaling in Carbohydrate and Energy Metabolism [O] . Kumar, Satish, Dey, Debleena, Hasan, Gaiti 2011

机译：果蝇InsP3受体突变体幼虫中的基因表达模式揭示了InsP3信号在碳水化合物和能量代谢中的作用。

Patterns of Gene Expression in Drosophila InsP3 Receptor Mutant Larvae Reveal a Role for InsP3 Signaling in Carbohydrate and Energy Metabolism

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