Microrna-221 and Microrna-222 Modulate Differentiation and Maturation of Skeletal Muscle Cells

摘要

BackgroundMicroRNAs (miRNAs) are a class of small non-coding RNAs that have recently emerged as important regulators of gene expression. They negatively regulate gene expression post-transcriptionally by translational repression and target mRNA degradation. miRNAs have been shown to play crucial roles in muscle development and in regulation of muscle cell proliferation and differentiation.