166. Comparison of Oral Fluoroquinolones to Alternative Oral Agents for Definitive Step-Down Therapy in Gram-Negative Bloodstream Infections

摘要

BackgroundDuring the management of Gram-negative bloodstream infections (GN BSIs), definitive oral step-down therapy is often utilized. Fluoroquinolones (FQs) are commonly utilized due to excellent bioavailability; however, comparative evidence to oral trimethoprim/sulfamethoxazole (TMP/SMX) or β-lactams (BLs) are limited.